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DISA (Dual Isotope Simultaneous Acquisition)
DISA Cardiac
Study
General Information:
Cardiac DISA
(Dual Isotope Simultaneous Acquisition -MIBI/FDG)
studies are done at
the FuWai Hospital, Beijing,
China, 3 days a week. On each of these days, 5 - 8
Cardiac DISA studies are acquired and processed. The
DISA protocol is a unique GE
Nuclear Medicine feature
available on VG camera systems. The DISA
functionality,
collimator and protocol was developed
with Dr. M. Sandler & J. Patton, PhD, from
Vanderbilt University.
Imaging Procedure:
Following the
injection of 25 mCi Tc99m Sestamibi and 5 mCi F-18 FDG,
Dual Isotope
Simultaneous Acquisition (DISA) SPECT
was performed with the Millennium VG5
Hawkeye camera.
Projections were acquired for ~ 25 minutes in 90?? mode
using the
DISA collimator. The images were
reconstructed using FBP and three orthogonal
planes
were prepared for each isotope.
Findings:
Tc99m Sestamibi images
demonstrate a large antero apical area of
decreased
activity suggesting myocardial scarring.
The cine display of projections does not
demonstrate
tissue attenuation. Intrinsically registered FDG images
of the same
orthogonal planes reveal homogeneous
distribution of FDG throughout the
myocardium.
Impression:
DISA: Tc99m
Sestamibi images indicate a perfusion defect in the
antero apical
myocardium. The F-18 FDG images show
uniform tracer distribution indicating
viable
myocardium. The Sestamibi / FDG mismatch
indicates ischemia in the antero-
apical
region.
Images courtesy of FuWai
Hospital, Beijing, China.
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